Practical theology represents one of several new classifications within theology in the Western and Christian world, focusing on the application and function of theological teachings in human life. Although this branch of theology has no precedent in the Islamic world, the emphasis on its practical and functional aspects can be found in Muslim intellectuals’ and religious reformers’ orientations and thoughts. This connection is particularly evident in religious pathology, where Muslim reformers have sought to identify the causes of the decline of Islamic civilization and find solutions by revisiting Islamic teachings and beliefs. Among contemporary Islamic intellectuals, Martyr Morteza Motahhari, especially in the latter half of his life, has shown significant concern for this area, striving in most of his works to present an accurate understanding of Islamic teachings, which he believed have been misunderstood. After explaining the link between practical theology and religious reform, as well as the efforts of religious reformers in the pathology of religious beliefs and convictions, the author focuses on Motahhari and his works as a case study, eventually citing examples from his works.